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T6047Ralimetinib dimesylateRalimetinib Mesylate;LY2228820 dimesylate;Ralimetinib;LY2228820
Ralimetinib Mesylate is the dimesylate salt form of LY2228820, a tri-substituted imidazole derivative and orally available, p38 mitogen-activated protein kinase (MAPK) inhibitor with potential anti-inflammatory and antineoplastic activities.
价 格:¥电议型 号:T6047产 地:中国大陆
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T6045Torin 1
Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.
价 格:¥电议型 号:T6045产 地:中国大陆
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T6044Telotristat Etiprate特罗司他马尿酸盐;LX1606 (Hippurate);LX 1606 Hippurate
Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.
价 格:¥电议型 号:T6044产 地:中国大陆
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T6043PF-3845PF3845;PF 3845
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
价 格:¥电议型 号:T6043产 地:中国大陆
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T6042[11C]MP 10Mardepodect;PF-2545920
[11C]MP 10, a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.
价 格:¥电议型 号:T6042产 地:中国大陆
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T6041Oprozomib奥泼佐米;ONX 0912;PR-047
Oprozomib (ONX 0912) , an inhibitor for CT-L activity of 20S proteasome β5(IC50=36 nM)/LMP7(IC50=82 nM), is orally bioavailable. Oprozomib also has potential antineoplastic activity.
价 格:¥电议型 号:T6041产 地:中国大陆
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T6040Aloxistatin阿洛司他丁;E64c ethyl ester;Loxistatin;E64d
Aloxistatin is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with the ability to inhibit calpain activity i
价 格:¥电议型 号:T6040产 地:中国大陆
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T6038(-)-Blebbistatin(S)-(-)-Blebbistatin
(-)-Blebbistatin is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM.
价 格:¥电议型 号:T6038产 地:中国大陆
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T6037E-64E 64;E64;Proteinase inhibitor E 64
E-64 is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.
价 格:¥电议型 号:T6037产 地:中国大陆
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T6035Odanacatib奥达卡替;奥当卡替;MK-0822
Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.
价 格:¥电议型 号:T6035产 地:中国大陆
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T6034UMI-77UMI77;UMI 77
UMI-77, a specific Mcl-1 inhibitor (Ki: 490 nM), has selectivity over other members of Bcl-2 family.
价 格:¥电议型 号:T6034产 地:中国大陆
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T6033Zotarolimus佐他莫司;咗他莫司;ABT-578;A 179578
Zotarolimus, an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).
价 格:¥电议型 号:T6033产 地:中国大陆
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T6032BirabresibMK-8628;OTX015 (MK 8628/Birabresib);OTX-015
Birabresib is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4 with potential antineoplastic activity.
价 格:¥电议型 号:T6032产 地:中国大陆
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T6031GNE0877GNE-0877;GNE 0877
GNE-0877 is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).
价 格:¥电议型 号:T6031产 地:中国大陆
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T6030XL388
XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.
价 格:¥电议型 号:T6030产 地:中国大陆
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T6029ONX-0914ONX 0914;PR-957;ONX0914
ONX-0914 is an effective and specific immunoproteasome inhibitor, which has minimal cross-reactivity for the constitutive proteasome.
价 格:¥电议型 号:T6029产 地:中国大陆
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T6028PF 477736PF477736;PF 00477736;PF-477736;PF-736,PF-00477736
PF-477736 is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.
价 格:¥电议型 号:T6028产 地:中国大陆
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T6027Delanzomib德兰佐米;CEP-18770
CEP-18770 is an orally active inhibitor of the chymotrypsin-like activity of proteasome (IC50: 3.8 nM). It only marginally inhibits the tryptic and peptidylglutamyl activities of the proteosome.
价 格:¥电议型 号:T6027产 地:中国大陆
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T6026CPI-203CPI 203;CPI203
CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).
价 格:¥电议型 号:T6026产 地:中国大陆
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T6025Danoprevir丹诺普韦;R7227;ITMN-191;RO5190591;RG7227
Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).
价 格:¥电议型 号:T6025产 地:中国大陆