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T10238Aclacinomycin A hydrochloride;盐酸阿柔比星Aclarubicin hydrochloride;盐酸阿柔比星|||Aclarubicin hydrochloride
Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (chymotrypsin-like) activity of the 20S proteasome. Aclacinomycin A hydrochloride is also a dual inhibitor of topoisomerase I and II.
价 格:¥电议型 号:T10238产 地:中国大陆
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T10233Acetylarenobufagin;乙酰沙蟾毒精Acetylarenobufagin
Acetylarenobufagin is a steroidal hypoxia-inducible factor-1 (HIF-1) modulator.
价 格:¥电议型 号:T10233产 地:中国大陆
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T1022Hygromycin B;潮霉素BHygrovetine;潮霉素B|||Hygrovetine
Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis by interfering with translocation and causing mistranslation of the 70S ribosome. Hygromycin B can be used to screen prokaryotic or eukaryotic cells transfected with hph or hyg resistance genes.
价 格:¥电议型 号:T1022产 地:中国大陆
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T1020Doxorubicin hydrochloride;盐酸阿霉素Adriamycin|||Doxorubicin (Adriamycin) HCl|||Hydroxydaunorubicin hydro
Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitumor activity. Doxorubicin hydrochloride reduces the phosphorylation of AMPK and its downstream target protein acetyl coenzyme A carboxylase, and induces apoptosis and autophagy.
价 格:¥电议型 号:T1020产 地:中国大陆
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T101978,?9-?Epoxy-?3-?isobutyryloxy-?10-?(2-?methylbutanoyl)?thymol;8,9-环氧-3-异丁酰-10-(2-甲基丁酰) 百里草酚8-9-epoxy
8,9-Epoxy-3-isobutyryloxy-10-(2-methylbutanoyl)thymol is a chemical composition of essential oils from Telekia speciosa. It also shows marked antipro-liferative activity against human cancer cell lines in vitro.
价 格:¥电议型 号:T10197产 地:中国大陆
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T101967α-Hydroxy-4-cholesten-3-one;化合物 T101967α-Hydroxy-4-cholesten-3-one
7α-Hydroxy-4-cholesten-3-one is an intermediate in the synthesis of bile acids from cholesterol. It is a PXR agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss and other diseases associated with defective bile acid biosynthesis.It is the physiological substrate for CYP8B1.
价 格:¥电议型 号:T10196产 地:中国大陆
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T101957-O-Geranylscopoletin;化合物 T101957-Geranyloxy-6-methoxycoumarin;7-Geranyloxy-6-methoxycoumarin
7-O-Geranylscopoletin is a natural coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as the treatment of chronic rheumatism, antispasmodic, paralysis, hemiplegia, and stimulant.
价 格:¥电议型 号:T10195产 地:中国大陆
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T101947-Methylguanine;化合物 T101947-Methylguanine
7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents and used as a probe of DNA–protein interactions and a key component of the DNA sequencing method.
价 格:¥电议型 号:T10194产 地:中国大陆
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T10191L7-Chlorokynurenic acid;7-氯犬尿酸7-chloro-4-hydroxy-2-carboxyquinoline|||7-CKA;7-chloro-4-hydroxy-2-carb
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.
价 格:¥电议型 号:T10191L产 地:中国大陆
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T101856-Phosphogluconic acid;6-磷酸葡萄糖酸6-Phosphogluconic acid
6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI).The activity of phosphoglucose isomerase was inhibited intensely and competitively by 6-Phosphogluconic acid, with an apparent Ki of 0.048 mM for glucose 6-phosphate and 0.042 mM for fructose 6-phosphate as the substrate.
价 格:¥电议型 号:T10185产 地:中国大陆
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T101836-Methoxytricin;6-甲氧基哌啶6-Methoxytricin
6-Methoxytricin, a flavonoid isolated from Centella asiatica, is an inhibitor of aldose reductase (AR) and advanced glycosylation end-products (AGE), and inhibits T-cell proliferation and activation in biologic cells.
价 格:¥电议型 号:T10183产 地:中国大陆
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T101645,6-Dihydroxyindole;5,6-二羟基吲哚Dopamine lutine;Dopamine lutine
5,6-Dihydroxyindole (Dopamine lutine) is a melanin precursor and has a broad-spectrum antibacterial, antiviral, antifungal, antiparasitic activity. It has cytotoxic effects and is strongly toxic against various pathogens.
价 格:¥电议型 号:T10164产 地:中国大陆
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T1016D-α-Tocopherol acetate;乙酸维生素EVitamin E Acetate|||Tocopherol acetate;乙酸维生素E|||Vitamin E Acetate|||Toc
D-alpha-Tocopherol acetate (Vitamin E Acetate) is hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine.
价 格:¥电议型 号:T1016产 地:中国大陆
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T101534-O-Methyl honokiol;4--O-甲基和厚朴酚4-O-Methyl honokiol
4-O-Methyl honokiol, a natural neolignan isolated from Magnolia officinalis, acts as a PPARγ agonist and inhibits NF-κB activity, used for cancer and inflammation research.
价 格:¥电议型 号:T10153产 地:中国大陆
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T101484-Hydroxynonenal;4-羟基壬烯醛4-HNE;4-羟基壬烯醛|||4-HNE
4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).
价 格:¥电议型 号:T10148产 地:中国大陆
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T101464-Hydroxyderricin;4-羟基德里辛4-Hydroxyderricin
4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-hydroxylase (DBH) activity and possesses antidepressant activity.
价 格:¥电议型 号:T10146产 地:中国大陆
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T101123-Hydroxy-4-methoxyacetophenone异香草乙酮Acetoisovanillone|||4-甲氧基-3-羟基苯乙酮|||异香草乙酮
3-Hydroxy-4-methoxyacetophenone (Acetoisovanillone) is an active P. spinosa extract. It possesses anti-inflammatory activity and prevented injuries due to administration of acetic acid in the colon.
价 格:¥电议型 号:T10112产 地:中国大陆
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T1011Itraconazole;伊曲康唑R51211;伊曲康唑|||R51211
Itraconazole (R51211) belongs to the triazole group of natural products and is an antifungal agent with oral activity. Itraconazole is a Hedgehog signaling pathway antagonist, an oxysterol-binding protein (OSBP) inhibitor, and an inhibitor of cytochrome P-450-dependent enzymes.
价 格:¥电议型 号:T1011产 地:中国大陆
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T101093-Carene;3-蒈烯Delta-3-Carene;Delta-3-Carene
3-Carene(Delta-3-Carene) is a bicyclic monoterpene extracted from western larch and Douglas-fir that acts as a phytofungicide.3-Carene inhibits inflammatory infiltrates and COX-2 overexpression induced by nociceptive stimuli.3-Carene has anti-injury properties and promotes the activity and expression of alkaline phosphatase, an early marker of osteoblast differentiation.
价 格:¥电议型 号:T10109产 地:中国大陆
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T101053α-Hydroxymogrol;3α-羟基罗汉果醇3α-Hydroxymogrol
3α-Hydroxymogrol is a triterpenoid isolated from Siraitia grosvenorii Swingle. It is a potent AMPK activator and enhances AMPK phosphorylation.
价 格:¥电议型 号:T10105产 地:中国大陆