尿酸酶(Uricase，EC1.7.3.3)又叫做尿酸氧化酶，由黑曲霉、黄曲霉等发酵液提取而得，白色冻干粉或灰白色至褐绿色结晶或光亮透明片状物，微溶于碱性缓冲液，pH值6.3，酶活性受清-化-物抑制，抑制剂如Ag⁺，Hg²⁺。

由于尿酸难以溶解，浓度高时会沉积于组织内形成结石，因此尿酸酶在用于高尿酸血患者时，能降低血液中尿酸含量，增加尿中尿囊酸排泄，从而消除尿酸在血液和组织中的潴留。也用于测定血清及尿中的尿酸量。

本公司尿酸酶为基因重组产品，无动物源性病毒产品纯度高，活性好。

生化研究：能催化尿酸迅速氧化，*终生成尿囊酸。用于测定血清及尿中的尿酸量。

产品说明：

剂型：白色冻干粉或液体

保存缓冲液：20mM Tris，pH8.0

酶活：约 10U/mg 干粉

活力单位：在pH 8.5，37 °C的条件下，每分钟氧化1umol尿酸所需的酶的量定义为1个U单位。

基本信息：

来源：基因重组表达

分子量：45KDa左右（SDS-PAGE检测）

纯度：≥90%（SDS-PAGE检测）

保存条件：冻干粉-20度或4℃保存长期保存

运输条件：低温冰袋

安全提示： 不可用于人体实验

Uricase

Uricase (EC1.7.3.3) is also called urate oxidase, which is extracted from the fermentation liquid of Aspergillus niger ａnd Aspergillus flavus. It is made of white freeze-dried powder or gray to brownish green crystal or bright ａnd transparent flake, slightly soluble in alkaline buffer, with pH value of 6.3. The enzyme activity is inhibited by cyanide, ａnd the inhibiting agents such as Ag⁺, Hg²⁺.

Uric acid is difficult to dissolve. when it is high, it will deposit in the tissue to form calculus. Therefore, urase can reduce uric acid in blood ａnd increase urinic acid excretion in urine in patients with hyperuricemia, thereby eliminating the retention of uric acid in blood ａnd tissues, ａnd also determining the amount of uric acid in blood ａnd urine.

Uricase of our company is a recombinant product with high purity ａnd good activity.

Biochemical research: it can catalyze the rapid oxidation of uric acid to produce allantoic acid. It is used for the determination of urine acid in serum ａnd urine.

[Product Description]

Dosage form: white lyophilized powder or liquid

Storage buffer: 20mM Tris, pH8.0

Enzyme activity: about 10U/mg dry powder

Activity unit: at pH 8.5, 37 ° C, the amount of enzyme required to oxidize 1 umol of uric acid per minute is defined as 1 u unit.

General information:

Source: gene recombinant expression

Molecular weight: about 45KDa (SDS-PAGE detection)

Purity: ≥ 90% (SDS-PAGE detection)

Storage conditions: -20℃ for freeze dried powder or 4℃ for long-term storage

Transportation conditions: ice bag with low temperature

Safety tips: not for human experiment