产品编号KMPH1835
产品名称Recombinant Human ACE2 Protein, His Tag
分子名称ACE2
产品别称Angiotensin-converting enzyme 2, ACE2
物种Human
宿主HEK293 Cells
应用ELISA, WB
规格100ug, 1mg
来源A DNA sequence encoding the human ACE2 (NP_068576.1) (Gln18-Ser740) was expressed with a polyhistidine tag at the C-terminus.纯度≥95% as determined by SDS-PAGE.
内毒素水平< 1.0 EU per μg of the protein as determined by the LAL method.
缓冲体系Lyophilized from sterile PBS, pH 7.4.
产品背景Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the cell membranes of cells located in the lungs, arteries, heart, kidney, ａnd intestines. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II into angiotensin (1–7). ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II ａnd increasing Ang(1-7), making it a promising drug target for treating cardiovascular diseases. ACE2 also serves as the entry point into cells for some coronaviruses.
保存条件Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.