中文名：环(L-精氨酰甘氨酰-L-Α-天冬氨酰-D-酪氨酰-L-赖氨酰)
英文名：Cyclo(-Arg-Gly-Asp-D-Tyr-Lys)
cyclo(RGD-DTyr-K)
CYCLO(-ARG-GLY-ASP-D-TYR-LYS)
c(RGDyK)
CAS：217099-14-4
等电点(PI)：10.46
平均亲水性：1.675
pH=7.0时的净电荷数：1.98
疏水性值：-2.72
密度: 1.52±0.1 g/cm3(Predicted)
溶解度: Soluble in DMSO
储存条件: Store at -20°C
酸度系数(pKa): 4.01±0.10(Predicted)
性状：白色粉末状固体
Molecular formula：C27H41N9O8
Molecular weight：619.67
Purity：95%+
Appearance：solid/powder
Matters for use：
It is sensitive to light ａnd temperature. In order to use the reagent effectively, the material should always be kept in a low temperature dry condition, away from light, ａnd avoid frequent thawing ａnd freezing.
storage conditions:
Store at - 20 ℃ as much as possible. If conditions permit, the material can be treated under inert gas to obtain better stability of the reagent.
Packing specification：1g，5g，10g
Supplier：陕西新研博美生物科技有限公司
结构式：
产品介绍：
Cyclo(-Arg-Gly-Asp-D-Tyr-Lys)属于多肽试剂，RGD肽是指含有由Arg-Gly-Asp三个氨基酸组成的序列多肽，有直线肽和环肽之分。它们是许多细胞外基质蛋白（如VN、FN、FGN、胶原等）等小识别短肽序列。根据肽链的构成可将多肽分为同聚肽（Homomeric）和杂聚肽（Heteromeric）两大类，者完全由氨基酸组成，后者是由氨基酸部分和非氨基酸部分组成的，如糖肽。
Cyclo(RGDyK) 是一种有效的选择性 αVβ3 整联蛋白 (integrin) 抑制剂，IC50 为 20 nM。
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