英文名:PSMA I&T,PSMA I and T
化学式:C63H92IN11O23
分子量:1497.5(m.i.),1498.4(av.)
结构式:
反应机理:
PSMA I&T中的PSMA也被称为叶酸水解酶Ⅰ和谷氨酸羧肽酶Ⅱ,它是一种高表达的跨膜丝氨酸蛋白酶。PSMA检测的方法包括免疫组织化学、免疫荧光染色等。
PSMA I and PSMA T are two isoforms of prostate-specific membrane antigen (PSMA), a protein expressed on the surface of prostate cells. PSMA I and PSMA T refer to the enzymatic activity of PSMA, with PSMA I representing the intact protein and PSMA T representing a proteolytically cleaved form.
PSMA I and PSMA T have been studied as potential biomarkers for prostate cancer. PSMA I is expressed in normal prostate cells and is thought to play a role in cell proliferation and migration. However, PSMA T is thought to be more specific to prostate cancer cells because it is proteolytically cleaved from PSMA I in cancer cells but not in normal cells.
产品形式:
1.外观为固体/粉末
2.溶于大部分有机溶剂,溶于水
3.纯度标准95+,详情可在线咨询
保存建议:避免反复冻融,避光避湿保存,储液应该立即使用,-20℃以下冰冻。从冰箱取出产品后,置于室温回温至少30min-1h,再开盖,以避免受潮。
同类型试剂:
HYNIC-PSMA
Cyclo(Ala-Ser)
Cy3B 炔烃
Cy3B DBCO
Cyclo(Ala-Gln)
Cyclo(D-Val-L-Pro)
Cyclo(-Glu-Gly)
Cyclo(Ala-His)
Cy3B四嗪
Cy3B NHS 酯
Cyclo(D-Leu-L-Pro)
Cy3B TCO
Cy3.5 炔烃
Cyclo(-D-Ala-D-Ala)
Cy3.5 叠氮化物
tert-Butyl-DCL (PSMA inhibitor)
Cyclo(D-Phe-L-Pro)
ICG-TFP酯
iFluor 488 炔烃
Cyclo(-Tyr-Arg)
Cy3B PEG8 甲基四嗪
cyclo(Ser-Tyr)
cyclo(Ser-Ser)
iFluor 488 叠氮化物
iFluor 555 TCO
Cyclo(-Ala-Tyr)
Cyclo(Ala-Gly)
Cyclo(Ala-Glu)
DCL (PSMA inhibitor) (ACUPA)
NOTA-PSMA
cyclo(Pro-Val)
cyclo(-Pro-Tyr)