一、基本信息

【产品简介】：DBCO基于叠氮-炔环加成反应的点击化学,被广泛应用于有机化学、药物化学、化学生物学、分子生物学、细胞生物学等多学科域。环张力炔基如DBCO、BCN等可以在无铜催化的温和条件下实现叠氮-炔基的环加成,促进了点击化学在活生物体系中的应用。

DBCO-NHS酯是一种与胺反应的化合物,可用于修饰含胺分子(在水性介质中的溶解度有限)。它与伯胺(例如赖氨酸的侧链氨基或多肽的N端氨基)在中性或弱碱性pH下反应形成共价键。这类分子量小,将为被修饰的分子添加的间隔。

DBCO＇s click chemistry based on azide alkyne cycloaddition reaction is widely used in various fields such as organic chemistry, pharmaceutical chemistry, chemical biology, molecular biology, ａnd cell biology. The copper catalyzed azide acetylene click chemistry reaction is a good type of bioorthogonal reaction, but the copper catalyzed system has poor biocompatibility in biological systems. Cyclic tension alkyne groups such as DBCO ａnd BCN can achieve azide alkyne group cycloaddition under mild conditions without copper catalysis, promoting the application of click chemistry in living biological systems.

DBCO-NHS ester is a compound that reacts with amines ａnd can be used to modify amine containing molecules (with limited solubility in aqueous media). It reacts with primary amines (such as the side chain amino group of lysine or the N-terminal amino group of peptides) to form covalent bonds at neutral or weakly alkaline pH. This type of molecule has a small molecular weight ａnd will add spacing to the modified molecule.

【中文名】：二苯基环辛炔-氨基，二苯基环辛炔标记胺，氮杂二苯并环辛炔胺

【英文名】：DBCO-NH2，DBCO-Amine，Dibenzocyclooctyne-amine，DBCO-amine，ADIBO-NH2，ADIBO-Amine，ADIBO-amine

【CAS号】：1255942-06-3

【化学式】：C18H16N2O

【分子量】：276.34

【结构式】：

二、产品详情

【外观】：固体/粉末

【溶解性】：溶于大部分有机溶剂

【规格】：10mg、25mg、50mg（接受各种规格的定制服务，具体可以线上咨询）

【纯度】：95%+

【储存条件】：本品应密封避光，储存于阴凉、干燥、通风处，避免反复冻融，储液应该立即使用

【注意事项】：陕西新研博美生物科技有限公司提示，试剂仅用于科学研究或者工业应用等非医疗目的，非药用，非食用！

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