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徕卡CA19-9 (Sialyl Lewisa)
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详细内容
徕卡CA19-9 (Sialyl Lewisa)
Clone C241:5:1:4
7 mL BOND ready-to-use PA0424 P (HIER)
Antigen Background
CA19-9 is an epitope on the sialylated Lewisa carbohydrate structure.
Sialylated Lewisa plays a role in cell adhesion by acting as a functional ligand
for the inducible adhesion molecule E-selectin. CA19-9 and CA50 (carcinoma
associated mucin antigen) are useful serum markers in the diagnosis and
follow up of gastrointestinal and pancreatic cancers. In carcinoma of the
pancreas, it is reported that the immunohistochemical expression of both
CA19-9 and CA50 correlates with tumor differentiation where the strongest
staining is observed in well differentiated tumors. These two markers are also
reported in a number of benign lesions such as chronic pancreatitis.
Also available as a liquid concentrate, refer to page 101
Adenocarcinoma: immunohistochemical staining with BOND ready-to-use CA19-9 (Sialyl
Lewisa) (C241:5:1:4) using BOND Polymer Refine Detection.
Clone C241:5:1:4
7 mL BOND ready-to-use PA0424 P (HIER)
Antigen Background
CA19-9 is an epitope on the sialylated Lewisa carbohydrate structure.
Sialylated Lewisa plays a role in cell adhesion by acting as a functional ligand
for the inducible adhesion molecule E-selectin. CA19-9 and CA50 (carcinoma
associated mucin antigen) are useful serum markers in the diagnosis and
follow up of gastrointestinal and pancreatic cancers. In carcinoma of the
pancreas, it is reported that the immunohistochemical expression of both
CA19-9 and CA50 correlates with tumor differentiation where the strongest
staining is observed in well differentiated tumors. These two markers are also
reported in a number of benign lesions such as chronic pancreatitis.
Also available as a liquid concentrate, refer to page 101
Adenocarcinoma: immunohistochemical staining with BOND ready-to-use CA19-9 (Sialyl
Lewisa) (C241:5:1:4) using BOND Polymer Refine Detection.