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IL36 Effector Reporter Cell
| CBP74119 | |
| I. Background | |
| Interleukin (IL)-36 is an important mediator of inflammatory diseases and is part of the IL-1 family. The IL-36 subfamily consists of IL-36α, IL-36β, IL-36γ and IL-36 receptor antagonist (IL-36Ra). IL-36 mediates intracellular signal transduction through IL-36 receptor (IL-36R) and IL-1 receptor accessory protein (IL-1RAcP). | |
| II. Introduction | |
| Expressed gene: | IL36R |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Synonym(s): | Interleukin-36γ, IL-1F, IL-1ε (epsilon), IL-1H1 |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+10%FBS+800ug/ml hygromycin+1ug/ml puromycin+10ug/ml blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| III. Representative Data | |
Figure 1. IL36 Effector Reporter cells stimulated by IL36. | |
