产品展示
CBP60294 OVCAR3人卵巢腺癌细胞
点击次数：8发布时间：2023/5/7 11:48:35
更新日期：2023/5/7 11:48:35
所 在 地：
产品型号：CBP60294
优质供应
详细内容
| CBP60294 | |
| I. General information | |
| Synonyms: | OVCAR3 |
| Background: | The NIH:OVCAR-3 line was established in 1982 by T.C. Hamilton, et al. from the malignant ascites of a patient with progressive adenocarcinoma of the ovary. |
| Species: | Homo sapiens, human |
| Tissue: | ovary |
| Disease: | adenocarcinoma |
| Gender: | female， 60 years， Caucasian |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| DNA Profile: | Amelogenin: X CSF1PO: 11,12 D13S317: 12 D16S539: 12 D5S818: 11,12 D7S820: 10 THO1: 9,9.3 TPOX: 8 vWA: 17 Cobioer’s Cell Line Authentication Service |
| Culture Medium: | RPMI-1640+20%FBS+10ug/ml insulin We strongly suggest to purchase the complete medium from Cobioer. |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Receptor Expression: | Androgen receptor, positive; estrogen receptor, positive; progesterone receptor, positive |
| Tumor Formation: | Yes, Forms colonies in soft agar Yes, in nude mice inoculated subcutaneously with 107 cells Tumors developed within 21 days at 100% frequency 5/5. |
| Comments: | Forms colonies in soft agar and has an abnormal karyotype. Resistant to clinically relevant concentrations of adriamycin, melphalan and cisplatin. Both cultured cells and xenografts exhibit androgen and estrogen receptors. Xenograft models have been used to show that treatment with 17 beta estradiol can induce progesterone receptors in this human ovarian carcinoma. For more information, please contact Cobioer 4008-750-250. |
