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CBP73227 KRAS G12C/BaF3激酶
点击次数：6发布时间：2023/5/27 19:38:39
更新日期：2023/5/27 19:38:39
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产品型号：CBP73227
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详细内容
| CBP73227 | |
| I. Introduction | |
Cell Line Name： | KRAS G12C/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+1ug/ml puromycin |
Mycoplasma Status: | Negative |
| II.Background | |
KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118). | |
| III. Representative Data | |
1.WB of KRAS G12C/BaF3
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2.Sanger of KRAS G12C/BaF3
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3. Anti-proliferation assay | |
Figure 3. CTG Proliferation Assay of BaF3 KRAS G12C Cells (C3). | |
