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CBP73010 ETV6(Tel)-ARG/BaF3激酶
点击次数:13发布时间:2023/7/1 10:27:55
更新日期:2023/7/1 10:27:55
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产品型号:CBP73010
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详细内容
CBP73010 | |
I. Introduction | |
Cell Line Name: | ETV6(Tel)-ARG/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+2ug/ml puromycin |
Mycoplasma Status: | Negative |
II.Background | |
ETV6, ets variant 6, is a member of the ETS family of transcription factors, which functions as a transcriptional repressor and is involved in hematopoietic differentiation (PMID: 16828711). Fusions of ETV6 with various partners are frequently associated with hematological cancers (PMID: 22578774) and ETV6 mutations have been identified in acute lymphoblastic leukemia (PMID: 22162831) and acute myeloid leukemia (PMID: 18305557). | |
III. Representative Data | |
Figure 1. CTG Proliferation Assay of BaF3 TEL-ARG Cells (C1). |