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CBP74071 TL1A/CHO细胞
点击次数：4发布时间：2023/7/6 10:34:57
更新日期：2023/7/6 10:34:57
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产品型号：CBP74071
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详细内容
| CBP74071 | |
| I. Background | |
| Tumor necrosis factor (TNF)-like cytokine 1A (TL1A)/TNF superfamily member 15 (TNFSF15) is a proinflammatory cytokine and a member of the TNFα superfamily, as it was originally characterized in a screen for novel molecules with homology to TNFα. | |
| II. Description | |
| TL1A is expressed on activated T cells, dendritic cells, and monocytes, as well as induced by TNFα and interleukin (IL)1α in Huvec cells in vitro.In contrast to the TNFα receptors, which are expressed on essentially all cells, the receptor for TL1A, death receptor 3 (DR3), is primarily expressed on T cells, natural killer (NK) cells, and NK T (NKT) cells, thereby limiting the effects of TL1A. | |
| III. Introduction | |
| Host Cell: | CHO |
| Expressed gene: | TL1A |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+600ug/ml hygromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Ligand of DR3&Binding Assay,FACS |
| IV. Description of Host Cell Line | |
| Organism: | Cricetulus griseus, hamster, Chinese |
| Tissue: | Ovary |
| Disease: | Hamster Chinese ovary |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| Ⅴ. Representative Data | |
Figure 1.Recombinant CHO-cells constitutively expressing TL1A. | |
