hypersil gold aq™ is built upon the technology of the hypersil gold™ silica, ensuring optimized peak shape, and therefore, resolution, sensitivity and efficiency. because hypersil gold aq is a polar endcapped c18 phase, it also offers superior retention of polar compounds. dispersive interactions are the primary mechanism of retention with alkyl chain bonded phases. the polar functional group used to endcap hypersil gold aq provides an additional interaction mechanism by which polar compounds can be retained and resolved. this additional interaction mechanism may often provide se-lectivity differences over the traditional alkyl chain chemistries, and offers a solution for the separation of polar compounds which exhibit insufficient retention on pure alkyl chain phases under typical reversed phase mobile phase conditions. |