hypurity advance contains a polar amide group embedded within a c8 chain, and is fully endcapped. the columns are based on our metal free hypurity silica and, compared to other phases, produces a competely new se-lectivity. a polar functional group between alkyl ligands and the silica surface allows faster analysis without compromising the resolving power. hypurity advance - resulting in exceptional chromatographic performance. the phase chemistry allows three interaction mechanismswith samples:
the polar character assists retention of polar compounds and limits interactions of samples with the silica surface - which reduces retention of basic compounds.
this effect often resukts in a completely new elution order when compared to traditional alkyl bases chemistries, and gives the columns complete stability in 100% aqueous mobile phases.
the c8 ligand gives moderate retention for neutral samples, hence hypuritry advance is ideal for high throughoput laboratories with complex and variable sample types.
other column dimensions and hardware designs are available. please contact us for more information if you do not see the exact column that you are interested in.
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