产品类别 产品目录 >> 一抗 >> 一抗
产品编号 bs-2250R
英文名称 Anti-Integrin alpha V/CD51
中文名称 整合素αV抗体
别 名 fibronectin receptor alpha; ITGAV; CD51; DKFZp686A08142; MSK8; Msk 8; VNR; similar to Inte... 更多>>
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 hu, rat, mo
产品类型 一抗
研究领域 心血管 信号转导 细胞膜受体 细胞粘附分子
蛋白分子量 predicted molecular weight: 128kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Integrin alpha V C-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
产品应用 WB=1:1000-10000 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-100 IF=1:50-200
（石蜡切片需做抗原修复） not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 Integrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, ａnd platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, ａnd beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment ａnd spreading on vitronectin ａnd other matrix components. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi＇s sarcoma lesions. Alpha-V/beta-6 binds to foot-and-mouth disease virus （FMDV） VP1 protein ａnd acts as a receptor for this virus By similarity. Alpha-V/beta-6 binds to coxsackievirus A9 ａnd coxsackievirus B1 capsid proteins ａnd acts as a receptor for these viruses. 整合素αV抗体 的相关抗体产品： bs-1960R Anti-ABCF1 ATP结合盒蛋白家族GCN20F家族1抗体 bs-1231R Anti-ABCG1 三磷酸腺苷结合盒亚家族G1抗体 bs-0662R Anti-ABCG2 三磷酸腺苷结合转运蛋白G超家族成员2抗体 bs-1727R Anti-ABCG4 ABC膜转运蛋白抗体 bs-5013R Anti-ABCG5 三磷酸腺苷结合转运蛋白G超家族成员5抗体 bs-5014R Anti-ABCG8 三磷酸腺苷结合转运蛋白G超家族成员8抗体 bs-0583R Anti-c-Abl 非受体酪氨酸激酶c-Abl抗体 bs-3032R Anti-phospho-c-Abl（Tyr412） 磷酸化非受体酪氨酸激酶c-Abl抗体 bs-3041R Anti-phospho-c-Abl（Tyr245） 磷酸化非受体酪氨酸激酶c-Abl抗体
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