药理活性: Antineoplastic （mus, in vivo,Lewis lung cancer ａnd W256）; cytotoxic （KB in vitro, ED50 = 3~28μg/mL）;cytotoxic （HeLa, IC50 = 30.4μg/mL, control Mitomycin C, IC50 =

1.7μg/mL）; cytotoxic （number of tumor cell lines, antiproliferative,induces differentiation of HL-60 cells in vitro in aconcentration-dependentmanner）; cytotoxic （inhibits invasion of mus MO4 cells into embryonicchick heart fragments in vitro）; antifungal （Deuterophoma tracheiphila）;antithrombotic; platelet aggregation inhibitor （rat, orl, in vivo）;anti-inflammatory （Ungar method, ED25 = 20mg/kg, intensity ofanti-inflammation 50u/g）; anti-inflammatory （modulator of cytokine network:modulator of cytokine network: effectively inhibits production of PGE2 andproMMP-9 in rabbit synovial fibroblasts）; anti-inflammatory（suppresses IL-1β-induced production of PGE2 in hmn synovial fibroblasts,IC50 < 4μmol/L; decreases expression of IL-1α, IL-1β, TNF-α ａnd IL-6mRNAs in J774A.1 macrophages at 32μmol/L; a suggested lead compoundto develop novel anti-inflammatory or immunomodulatory drugs

上海一林生物科技有限公司主营中药对照品,标准品,植物单体,细胞筛选用植物提取物。

我们服务的方向:

1.天然药物化学（包括海洋药物）

各种纯度植物单体,提取物,天然产物系列单体提取分离定制服务。

2.药物分析鉴定      

供应多种色谱级中药对照品。

3.药理学    

多种高纯度中药活性成分和小包装植物提取物供药理筛选和动物实验。如需大量产品,可提供定制服务。

4.药物化学

多种中药活性成分供结构改造

5.药厂

大量中药活性成分,中药对照品,如需大量产品,可定制,同时提供产品工艺研发服务