产品展示
Amfebutamone Hydrochloride31677-93-7 盐酸安非他酮
点击次数：151发布时间：2016/7/1 15:15:19
更新日期：2024/9/19 16:50:29
所 在 地：中国大陆
产品型号：
优质供应
详细内容
盐酸安非他酮
分子式： C13H18ClNO.HCl 分子量：276.20
产品描述
Amfebutamone (Bupropion)是一种选择性去甲肾上腺素-多巴胺再摄取的抑制剂，IC50分别为6.5 和 3.4μM
靶点
IC50
生物活性
Amfebutamone (Bupropion) is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 ａnd 3.4µM for the reuptake of dopamine ａnd norepinephrine, respectively. Its primary pharmacological action is Norepinephrine-dopamine reuptake inhibition. It binds selectively to the dopamine transporter, but its behavioural effects have often been attributed to its inhibition of norepinephrine reuptake. It also acts as a nicotinic acetylcholine receptor antagonist.
溶解性
DMSO 8 mg/mL，水 <1 mg/mL，乙醇 <1 mg/mL
稳定性
2年 -20°C粉状，6月-80°C溶于DMSO
