产品展示
钠通道蛋白α ENaC,Anti-Alpha-ENaC,一抗
点击次数:192发布时间:2012/6/17 13:17:46
更新日期:2013/5/6 17:18:34
所 在 地:其它
产品型号:
优质供应
详细内容
--产品介绍:Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.Subcellular Location : Apical cell membrane; Multi-pass membrane protein.Tissue Specificity : Highly expressed in kidney and lung. Detected at intermediate levels in pancreas and liver, and at low levels in heart and placenta. Isoform 1 and isoform 2 predominate in all tissues. Expression of isoform 3, isoform 4 and isoform 5 is very low or not detectable, except in lung and heart.Similarity : Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1A subfamily.Subunit : Probable heterotrimer containing one alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit. Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2.αENaC
(1mg/1ml钠通道蛋白α ENaCAnti-Alpha-ENaC,的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
--钠通道蛋白α ENaC的参数标准:
浓度:1mg/1ml
交叉反应:hu, mo, rat, dog, pig, cow, hrs, shp
产品类型:一抗
研究领域:神经生物学信号转导细胞膜受体
蛋白分子量:predicted molecular weight: 76kDa
性状:Lyophilized or Liquid
免疫原:KLH conjugated synthetic peptide derived from human Alpha-ENaC
亚型:polyclonal
纯化方法:affinity purified by Protein A
储存液:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用:WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500Flow-Cyt=1:100-500IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
上海田源专业销售钠通道蛋白α ENaC抗体产品,详细抗体目录请访问:http://www.app17.com/c68810/products/t87312.html