腺苷酸环化酶1抗体Anti-ADCY1/Adenylyl cyclase的产品详细说明：

－－产品介绍：The membrane bound adenylyl cyclases （ACs） represent one of the major families of effector enzymes for G protein coupled receptors. Eight human AC isoforms （AC-1 through AC-4） have been identified up to now ａnd genes for at least nine adenylate cyclase （AC-1-AC-9） have been cloned characterized ａnd sequenced.This is a calmodulin-sensitive adenylyl cyclase which may be involved in regulatory processes in the central nervous system. It may play a role in neuronal plasticity, memory acquisition ａnd learning ａnd is expressed predominantly in the brain, retina ａnd adrenal medulla.腺苷酸环化酶（adenylate cyclase, AC） 是G蛋白偶联受体家族，是膜整合蛋白,它的氨基端和羧基端都朝向细胞质。AC在膜的细胞质面有两个催化结构域,还有两个膜整合区,每个膜整合区分别有6个跨膜的α螺旋。哺乳动物中已发现6个腺苷酸环化酶异构体。由于AC能够将ATP转变成cAMP,引起细胞的信号应答,因此,腺苷酸环化酶是G蛋白偶联系统中的效应物。

（1mg/1ml腺苷酸环化酶1抗体Anti-ADCY1/Adenylyl cyclase，的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

－－腺苷酸环化酶1抗体的参数标准：
浓度：1mg/1ml
交叉反应：hu, rat, mo
产品类型：一抗
研究领域：肿瘤细胞生物免疫学神经生物学信号转导转录调节因子激酶和磷酸酶
蛋白分子量：predicted molecular weight: 127-130kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human Adenylyl cyclase
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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