肌动蛋白α（α-SMA）抗体Anti-Actin α/alpha-SMA的产品详细说明：

－－产品介绍：Actin alpha 2, the human aortic smooth muscle actin gene, is one of six different actin isoforms which have been identified.Actins are highly conserved proteins that are involved in cell motility, structure ａnd integrity. Alpha actins are a major constituent of the contractile apparatus.结构蛋白（Structural Proteins）Actin α/α-Actin 是一种具有收缩能力的微丝蛋白，a-SMA广泛分布于几乎所有的肌型细胞中。Actin-α蛋白主要用于检测骨骼肌、平滑肌、血管平滑肌、心肌和肌原性肿瘤 包括：平滑肌瘤、平滑肌肉瘤、横纹肌肉瘤以及肌上细胞和肌上皮瘤。Actin（肌动蛋白）是在所有真核细胞中都表达的高度保守的蛋白质。它们沿微管组成了细胞骨架的主要成分。肌动蛋白至少表达为6种异构形式。它在心脏、骨骼横纹肌组织和某些平滑肌组织中表达，调节其收缩功能。有报导说肌动蛋白在乳房瘤中是高度磷酸化的。肌动蛋白的功能失调也会导致某种类型的心脏病。平滑肌α肌动蛋白使人更感兴趣，因为编码它的基因是相对局限于在血管平滑肌细胞中表达的少数几个基因。肌动蛋白是标记平滑肌和肌上皮细胞肿瘤的工具。

（1mg/1ml肌动蛋白α（α-SMA）抗体Anti-Actin α/alpha-SMA，的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

－－肌动蛋白α（α-SMA）抗体的参数标准：
浓度：1mg/1ml
交叉反应：hu, mo, rat, cat, chk, cow, dog, Fsh, Gpig, Hm, Mmot, Op, pig, Rb, shp
产品类型：一抗
研究领域：肿瘤细胞生物免疫学细胞骨架
蛋白分子量：predicted molecular weight: 42kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human Actin alpha C-terminus
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

上海田源专业销售肌动蛋白α（α-SMA）抗体抗体产品，详细抗体目录请访问：http://www.app17.com/c68810/products/t87312.html