突触结合蛋白1抗体Anti-Synaptotagmin 1/SYT1的产品详细说明：

－－产品介绍：The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca（2+） sensors in the process of vesicular trafficking ａnd exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first C2 domain mediates Ca（2+）-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group ａnd a diacyl backbone. A Ca（2+）-dependent interaction between synaptotagmin ａnd putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca（2+）-independent manner; these are neurexins, syntaxin ａnd AP2.

（1mg/1ml突触结合蛋白1抗体Anti-Synaptotagmin 1/SYT1，的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

－－突触结合蛋白1抗体的参数标准：
浓度：1mg/1ml
交叉反应：hu, mo, rat, chk, Rb, dog, cow, pig
产品类型：一抗
研究领域：肿瘤免疫学神经生物学信号转导细胞粘附分子
蛋白分子量：predicted molecular weight: 65kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human Synaptotagmin 1
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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