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--产品介绍:Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.乳腺球蛋白是一个乳腺相关糖蛋白,它是一个分泌素家族(包括子宫球蛋白和lipophilin)成员的远亲。与其他分泌素家族成员不同,乳腺球蛋白的mRNA在乳腺组织中特异表达。在石蜡组织切片的检测中,该抗体检测乳腺癌组织中的乳腺珠蛋白敏感度高达80%。当和其他乳腺特异标记如GCDFP-15联合应用时,检测乳腺珠蛋白敏感度高达84%。有资料表明检测乳腺球蛋白,在鉴定原发癌是否发生转移中起到至关重要的作用。
(1mg/1ml乳腺珠蛋白1抗体Anti-Mammaglobin A (mouse),的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
--乳腺珠蛋白1抗体的参数标准:
浓度:1mg/1ml
交叉反应:mouse
产品类型:一抗
研究领域:肿瘤细胞生物免疫学结合蛋白
蛋白分子量:predicted molecular weight: 8.5kDa
性状:Lyophilized or Liquid
免疫原:KLH conjugated synthetic peptide derived from mo Mammaglobin A (mouse)
亚型:polyclonal
纯化方法:affinity purified by Protein A
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用:WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
上海田源专业销售乳腺珠蛋白1抗体抗体产品,详细抗体目录请访问:http://www.app17.com/c68810/products/t87312.html