产品展示
肿瘤坏死因子α转换酶,Anti-ADAM17/CD156b,一抗
点击次数:180发布时间:2012/6/17 13:19:38
更新日期:2013/5/6 17:19:59
所 在 地:其它
产品型号:
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详细内容
--产品介绍:This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq].Subcellular Location : Membrane.Tissue Specificity : Ubiquitously expressed. Expressed at highest levels in adult heart, placenta, skeletal muscle, pancreas, spleen, thymus, prostate, testes, ovary and small intestine, and in fetal brain, lung, liver and kidney.Similarity : Contains 1 disintegrin domain.Contains 1 peptidase M12B domain.Subunit : Interacts with MAD2L1, MAPK14 and MUC1.
(1mg/1ml肿瘤坏死因子α转换酶Anti-ADAM17/CD156b,的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
--肿瘤坏死因子α转换酶的参数标准:
浓度:1mg/1ml
交叉反应:hu, mo, rat, Rb, dog, cow, pig
产品类型:一抗
研究领域:肿瘤免疫学神经生物学信号转导转录调节因子
蛋白分子量:predicted molecular weight: 68/93kDa
性状:Lyophilized or Liquid
免疫原:KLH conjugated synthetic peptide derived from human ADAM17
亚型:polyclonal
纯化方法:affinity purified by Protein A
储存液:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用:WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500Flow-Cyt=1:100-500IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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