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--产品介绍:Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptable to bacteria infection.Subcellular Location : Secreted.Tissue Specificity : Plasma.补体(complement,C)是由近20种不同血清蛋白组成的多分子系统,约占血清球蛋白总量的10%。补体在血清中的含量相对稳定,不因免疫应答而增加,仅在某些病理情况下才会发生波动。补体系统的基本组成包括9种血清蛋白成分,按发现的先后顺序而分别命名为C1-9。C3是一种β球蛋白,是补体中含量*多、作用*重要的一个组分,是补体两条主要激活途径的中心环节,有重要的生物活性作用,可在肝脏中产生。C3蛋白由α、β2条肽链经二硫键连接而成,本产品能特异性的识别C3的β链。
(1mg/1ml补体C3b抗体Anti-Complement C3 beta chain,的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
--补体C3b抗体的参数标准:
浓度:1mg/1ml
交叉反应:hu
产品类型:一抗
研究领域:细胞生物免疫学淋巴细胞
蛋白分子量:predicted molecular weight: 187kDa
性状:Lyophilized or Liquid
免疫原:KLH conjugated synthetic peptide derived from hu Complement C3 beta chain
亚型:polyclonal
纯化方法:affinity purified by Protein A
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用:WB=1:100-500ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500Flow-Cyt=1:20-100IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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