产品展示
活性依赖的神经保护肽抗体,Anti-ADNP/NAP,一抗
点击次数:158发布时间:2012/6/17 20:34:17
更新日期:2013/5/6 17:21:13
所 在 地:其它
产品型号:
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详细内容
--产品介绍:The activity dependent neuroprotective protein (ADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers. ADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells. ADNP is implicated in maintaining cell survival, perhaps through modulation of p53. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. 是一个潜在的转录调节因子,参与正常细胞与肿瘤细胞的增殖调控。广泛分布于大脑、小脑等组织,在肺、肾、小肠以及睾丸等组织也有微弱的表达。对体外培养的glia缺失神经元细胞有保护作用.
(1mg/1ml活性依赖的神经保护肽抗体Anti-ADNP/NAP,的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
--活性依赖的神经保护肽抗体的参数标准:
浓度:1mg/1ml
交叉反应:hu, mo, rat, dog, cow, chk
产品类型:一抗
研究领域:细胞生物神经生物学细胞凋亡转录调节因子
蛋白分子量:predicted molecular weight: 114kDa
性状:Lyophilized or Liquid
免疫原:KLH conjugated synthetic peptide derived from human ADNP N-terminus
亚型:polyclonal
纯化方法:affinity purified by Protein A
储存液:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用:WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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