产品展示
腺苷受体A3抗体,Anti-ADORA3,一抗
点击次数:168发布时间:2012/6/17 20:34:20
更新日期:2013/5/6 17:21:13
所 在 地:其它
产品型号:
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详细内容
--产品介绍:This ADORA3 gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. And may play a role in remodelling after myocardial cell injury; may be involved in male reproduction.Subcellular Location : Cell membrane; Multi-pass membrane protein.Similarity : Belongs to the G-protein coupled receptor 1 family.ADORA-3(腺苷受体A3)属于G蛋白偶联受体家族,在腺苷调节细胞活力和生长中起关键作用,并且在很多肿瘤中表达增高,A3AR可能成为肿瘤诊断标志物和治疗靶点。
(1mg/1ml腺苷受体A3抗体Anti-ADORA3,的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
--腺苷受体A3抗体的参数标准:
浓度:1mg/1ml
交叉反应:hu, rat, mo, pig, dog, cow, shp, Rb
产品类型:一抗
研究领域:心血管神经生物学细胞膜受体G蛋白偶联受体
蛋白分子量:predicted molecular weight: 35kDa
性状:Lyophilized or Liquid
免疫原:KLH conjugated synthetic peptide derived from human ADORA3 C-terminus
亚型:polyclonal
纯化方法:affinity purified by Protein A
储存液:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用:WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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