组蛋白去甲基化酶JARID1B抗体Anti-KDM5B/PLU1/Jarid1B的产品详细说明：

－－产品介绍：Histone demethylase that demethylates ＇Lys-4＇ of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 ＇Lys-9＇ or H3 ＇Lys-27＇. Demethylates trimethylated, dimethylated ａnd monomethylated H3 ＇Lys-4＇. Acts as a transcriptional corepressor for FOXG1B ａnd PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 ａnd HOXA5. In contrast, may act as a tumor suppressor for melanoma.

（1mg/1ml组蛋白去甲基化酶JARID1B抗体Anti-KDM5B/PLU1/Jarid1B，的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

－－组蛋白去甲基化酶JARID1B抗体的参数标准：
浓度：1mg/1ml
交叉反应：hu, mo
产品类型：一抗
研究领域：肿瘤细胞生物染色质和核信号表观遗传学
蛋白分子量：predicted molecular weight: 190 .kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human KDM5B/PLU1/Jarid1B
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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