产品展示
上海现货雌激素相关受体β抗体,Anti-ERRB2/Estrogen Related Receptor beta,一抗
点击次数:223发布时间:2012/6/18 14:20:34
更新日期:2013/5/6 17:24:20
所 在 地:其它
产品型号:
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详细内容
--产品介绍:Estrogen related receptor beta, a NR3 Steroid Receptor, has been shown to affect early placental development. Also it can act as a repressor of transcriptional activity mediated by the glucocorticoid receptor (GR). It binds as a monomer to the extended half-site TNAAGTGCA and as a homodimer to the estrogen response element (ERE), palindromic thyroid hormone response element (TRE(pal)), and SF-1 response element, but not to the glucocorticoid response element (GRE). Estrogen related receptor beta mutations lead to abnormal development of the chorion and defective diploid trophoblast proliferation, and are lethal during midgestation. Expression has been documented in mice in the extraembryonic ectoderm that gives rise to the chorion. ESTs have been isolated from normal human eye, lung, and testis libraries. The ligand for the receptor is PPARgamma coactivator 1 (PGC-1) beta.Subcellular Location : Nuclear
(1mg/1ml雌激素相关受体β抗体Anti-ERRB2/Estrogen Related Receptor beta,的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
--雌激素相关受体β抗体的参数标准:
浓度:1mg/1ml
交叉反应:hu, mo, rat, cow, hrs, dog, pig, Rb, Gpig, chk
产品类型:一抗
研究领域:肿瘤细胞生物发育生物学染色质和核信号信号转导转录调节因子
蛋白分子量:predicted molecular weight: 56kDa
性状:Lyophilized or Liquid
免疫原:KLH conjugated synthetic peptide derived from human Estrogen Related Receptor beta
亚型:polyclonal
纯化方法:affinity purified by Protein A
储存液:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用:WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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