微管相关蛋白轻链3C抗体Anti-LC3C的产品详细说明：

－－产品介绍：A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation ａnd degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy （self-eating）, ａnd is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 ａnd is involved in the formation of autophagosomal vacuoles, called autophagosomes. There are three isoforms of human LC3 （named MAP1LC3A, MAP1LC3B, ａnd MAP1LC3C）, which exhibit different tissue distributions. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders ａnd cardiac pathologies, where LC3 is widely employed as a marker for autophagy.Subcellular Location : Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Tissue Specificity : Most abundant in placenta, lung ａnd ovary.Similarity : Belongs to the MAP1 LC3 family.Subunit : 3 different light chains, LC1, LC2 ａnd LC3, can associate with MAP1A ａnd MAP1B proteins.

（1mg/1ml微管相关蛋白轻链3C抗体Anti-LC3C，的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

－－微管相关蛋白轻链3C抗体的参数标准：
浓度：1mg/1ml
交叉反应：hu, Danio rerio
产品类型：一抗
研究领域：心血管信号转导细胞骨架细胞自噬
蛋白分子量：predicted molecular weight: 14/17kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human LC3C（52-61aa）
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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