鸟苷酸激酶GMK抗体Anti-GUK1/Guanylate kinase的产品详细说明：

－－产品介绍：Guanylate kinase catalyzes the transfer of phosphate from adenosine triphosphate （ATP） to guanosine monophosphate （GMP） or dGMP. This enzyme functions in the recovery of cGMP ａnd is, therefore, thought to regulate the supply of guanine nucleotides to signal transduction pathways. The GUK2 ａnd GUK3 isoforms are determined by separate loci. Brady et al. （1996） cloned human ａnd mouse cDNAs of GUK1. They stated that the guanylate kinases are targets for cancer chemotherapy ａnd are inhibited by the antitumor drug 6-thioguanine. They reported that the human gene codes for a protein of 197 amino acids with a mass of 21.7 kD. They found that the 1-kb message was ubiquitously expressed.

（1mg/1ml鸟苷酸激酶GMK抗体Anti-GUK1/Guanylate kinase，的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

－－鸟苷酸激酶GMK抗体的参数标准：
浓度：1mg/1ml
交叉反应：hu, mo, rat
产品类型：一抗
研究领域：肿瘤信号转导激酶和磷酸酶
蛋白分子量：predicted molecular weight: 22kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human GUK1/Guanylate kinase
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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