瞬时受体电位蛋白12抗体Anti-TRPV4/TRP12的产品详细说明：

－－产品介绍：The detection of noxious stimuli （chemical, mechanical, or thermal） occurs predominantly at the peripheral terminals of primary afferent neurons. This information is ultimately transmitted to the central nervous system to evoke appropriate protective reflexes. TRPV4 is a non selective calcium permeant, swell activated, cation channel probably involved in osmotic ａnd mechano sensitivity. Activation by exposure to hypotonicity within the physiological range, low pH, citrate ａnd phorbol esters exhibits an outward rectification. Once activated the channel seems to be regulated in a calmodulin dependent manner, with a negative feedback mechanism.

（1mg/1ml瞬时受体电位蛋白12抗体Anti-TRPV4/TRP12，的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

－－瞬时受体电位蛋白12抗体的参数标准：
浓度：1mg/1ml
交叉反应：hu, mo, rat
产品类型：一抗
研究领域：肿瘤细胞生物免疫学微生物学信号转导通道蛋白表观遗传学
蛋白分子量：predicted molecular weight: 98kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from hu TRPV4/TRP12
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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