醛固酮合成酶CYP11B2抗体Anti-CYP11B2的产品详细说明：

－－产品介绍：The steroid 11beta-hydroxylase gene, also designated Cyp11b-1, is a marker for the functional differentiation of cells in the zonae fasciculata reticularis. The deduced protein CYP11B1 consists of 466 amino acids containing a secretory signal, epidermal growth factor-like repeats, ａnd a proteolytically inactive cathepsin B-related sequence. A related protein, human aldosterone synthase （CYP11B2）, is involved in substrate recognition ａnd conversion, with a functionally significant residue 112 in the N-terminal region of human CYP11B2. The inherited disorder glucocorticoid-remediable aldosteronism iscaused by a chimeric gene duplication between the CYP11B1 ａnd CYP11B2 genes. This disorder is characterized by hyperaldosteronism ａnd high levels of 18-hydroxycortisol ａnd 18-oxocortisol, which are under ACTH control.Subcellular Location : Mitochondrion membrane.Similarity : Belongs to the cytochrome P450 family.

（1mg/1ml醛固酮合成酶CYP11B2抗体Anti-CYP11B2，的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

－－醛固酮合成酶CYP11B2抗体的参数标准：
浓度：1mg/1ml
交叉反应：hu, mo, rat, dog, hrs, cow, shp, Rb
产品类型：一抗
研究领域：心血管细胞生物免疫学
蛋白分子量：predicted molecular weight: 52kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human CYP11B2
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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