细胞膜钙ATP酶4抗体Anti-PMCA4/Calcium Pump PMCA4 ATPase的产品详细说明：

－－产品介绍：Plasma membrane-type Ca2+-ATPases （PMCAs） mediate the export of bivalent calcium ions from eukaryotic cells. As members of the P class of ion-motive ATPases, PMCAs are a functionally diverse group of proteins that are derived from alternatively spliced transcripts originating from four distinct genes, PMCA1, 2, 3, ａnd 4. The expression of different PMCA isoforms ａnd splice variants is regulated in a developmental, tissue- ａnd cell type-specific manner, ａnd with respect to the physiological needs of specific cell ａnd tissue types. Spatial ａnd temporal rates of resting intracellular Ca2+ concentrations ａnd Ca2+ signaling in eukaryotic cells are dependent on the array of PMCA isoforms that are expressed in concert with the rate of Ca2+ export. PMCA3 expression is confined to brain ａnd skeletal muscle. The PMCA4 gene is located on human chromosome 1q25 ａnd is ubiquitously expressed.Subcellular Location : Cell membrane.Tissue Specificity : Isoform XB is the most abundant isoform ａnd is expressed ubiquitously. Isoforms containing segment Z have only been detected in heart, while isoforms containing segment a have been found in heart, stomach ａnd brain cortex.

（1mg/1ml细胞膜钙ATP酶4抗体Anti-PMCA4/Calcium Pump PMCA4 ATPase，的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

－－细胞膜钙ATP酶4抗体的参数标准：
浓度：1mg/1ml
交叉反应：Hu, mo, rat, cow, dog, zebrafish
产品类型：一抗
研究领域：
蛋白分子量：predicted molecular weight: 130kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human PMCA4
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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