烟碱型乙酰胆碱受体α3抗体Anti-CHRNA3/AChRα3的产品详细说明：

－－产品介绍：Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine ａnd glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors （AChRs） are found at the postsynaptic membrane of the neuromuscular junction ａnd bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChR?, also known as LNCR2, PAOD2, NACHRA3 or CHRNA3, is a 505 amino acid multi-pass membrane protein that belongs to the ligand-gated ion channel receptor family ａnd may play a role in neurotransmission. Subcellular Location : postsynaptic cell membrane. Cell membrane.

（1mg/1ml烟碱型乙酰胆碱受体α3抗体Anti-CHRNA3/AChRα3，的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

－－烟碱型乙酰胆碱受体α3抗体的参数标准：
浓度：1mg/1ml
交叉反应：hu
产品类型：一抗
研究领域：细胞生物神经生物学信号转导通道蛋白细胞膜受体
蛋白分子量：predicted molecular weight: 57kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from hu CHRNA3/AChRα3
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用：WB=1:100-500ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.

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