产品展示
上海现货间隙连接蛋白30抗体,Anti-connexin-30,一抗
点击次数:248发布时间:2012/6/20 16:20:28
更新日期:2013/5/6 17:26:34
所 在 地:其它
产品型号:
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详细内容
--产品介绍:The connexin family of proteins form hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences between connexins arise from specific amino-acid substitutions in the most highly conserved domains: the transmembrane and extracellular regions. Connexin 30, also known as GJB6 (Gap junction beta 6), ED2, EDH, HED or DFNA3, is a 261 amino acid multi-pass membrane protein that localizes to the cell junction and belongs to the connexin family. Functioning as a hexamer with other connexin proteins, connexin 30 facilitates the diffusion of low molecular weight materials from one cell to another. Defects in the gene encoding connexin 30 are the cause of ectodermal dysplasia type 2 (ED2) and non-syndromatic sensorineural deafness autosomal dominant type 3 (DFNA3), the former of which is characterized by abnormal development of ectodermal structures (such as skin and nails).Subcellular Location : Plasma membrane.
(1mg/1ml间隙连接蛋白30抗体Anti-connexin-30,的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
--间隙连接蛋白30抗体的参数标准:
浓度:1mg/1ml
交叉反应:hu, mo, rat
产品类型:一抗
研究领域:细胞生物神经生物学信号转导细胞粘附分子
蛋白分子量:predicted molecular weight: 30kDa
性状:Lyophilized or Liquid
免疫原:KLH conjugated synthetic peptide derived from hu connexin-30
亚型:polyclonal
纯化方法:affinity purified by Protein A
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用:WB=1:100-500ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
上海田源专业销售间隙连接蛋白30抗体抗体产品,详细抗体目录请访问:http://www.chem17.com/st233816/erlist_675408.html