细胞膜钙转运ATP酶抗体Anti-PMCA360TIYO-上海田源公司

性能参数：－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－中文名称：细胞膜钙转运ATP酶抗体英文名称：Anti-PMCA别名：ATP2B1; ATP2B2; ATP2B3; ATP2B4; ATPase Ca++ transporting plasma membrane 1; ATPase Ca++ tr...产品货号：包装号：G320产地：中国大陆/进口产品商标/品牌：TIUE、TIYO、新试剂、田源试剂供应商：上海田源试剂、新试剂－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－

产品详细描述

产品介绍：Plasma membrane-type Ca2+-ATPases （PMCAs） mediate the export of bivalent calcium ions from eukaryotic cells. As members of the P class of ion-motive ATPases, PMCAs are a functionally diverse group of proteins that are derived from alternatively spliced transcripts originating from at least four distinct genes. The expression of different PMCA isoforms ａnd splice variants is regulated in a developmental, tissue- ａnd cell type-specific manner, ａnd with respect to the physiological needs of specific cell ａnd tissue types. Spatial ａnd temporal rates of resting intracellular Ca2+ concentrations ａnd Ca2+ signaling in eukaryotic cells are dependent on the array of PMCA isoforms that are expressed in concert with the rate of Ca2+ export.Subcellular Location : Cell membrane; Multi-pass membrane protein.Tissue Specificity : Mainly expressed in brain cortex. Found in low levels in skeletal muscle, heart muscle, stomach, liver, kidney ａnd lung. Isoforms containing segment B are found in brain cortex ａnd at low levels in other tissues. Isoforms containing segments X ａnd W are found at low levels in all tissues. Isoforms containing segment A ａnd segment Z are found at low levels in skeletal muscle ａnd heart muscle.Similarity : Belongs to the cation transport ATPase （P-type） （TC 3.A.3） family. Type IIB subfamily.

（1mg/1ml细胞膜钙转运ATP酶抗体Anti-PMCA，ATP2B1; ATP2B2; ATP2B3; ATP2B4; ATPase Ca++ transporting plasma membrane 1; ATPase Ca++ tr...的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

细胞膜钙转运ATP酶抗体的质量标准：－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－浓度：1mg/1ml交叉反应：hu, mo, rat, hrs, cow, dog产品类型：一抗研究领域：肿瘤细胞生物免疫学信号转导转录调节因子蛋白分子量：predicted molecular weight: 130kDa性状：Lyophilized or Liquid免疫原：KLH conjugated synthetic peptide derived from human PMCA亚型：polyclonal纯化方法：affinity purified by Protein A储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500Flow-Cyt=1:20-100IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－

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