piwi样4蛋白抗体Anti-PIWIL4HILI 2;HILI2;HIWI 2;HIWI2;Miwi 2 protein;Miwi2;PIWI;Piwi like 2;Piwi like ...
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性能参数：

中文名称：piwi样4蛋白抗体
英文名称：Anti-PIWIL4
别名：HILI 2;HILI2;HIWI 2;HIWI2;Miwi 2 protein;Miwi2;PIWI;Piwi like 2;Piwi like ...
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Plays a central role during spermatogenesis by repressing transposable elements ａnd prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs ａnd Piwi proteins ａnd govern the methylation ａnd subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism ａnd are primarily derived from transposons ａnd other repeated sequence elements. Associates with secondary piRNAs antisense ａnd PIWIL2/MILI is required for such association. The piRNA process acts upstream of known mediators of DNA methylation. Participates to a piRNA amplification loop. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation （By similarity）. May be involved in the chromatin-modifying pathway by inducing ＇Lys-9＇ methylation of histone H3 at some loci.

piwi样4蛋白抗体的质量标准：
浓度：1mg/1ml
交叉反应：human, moouse, Monkey
产品类型：一抗
研究领域：细胞生物发育生物学染色质和核信号转录调节因子表观遗传学
蛋白分子量：predicted molecular weight: 97kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from hu PIWIL4
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
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2、非质量报告提及的指标投诉

piwi样4蛋白抗体Anti-PIWIL4的相关产品目录：



（1mg/1mlpiwi样4蛋白抗体Anti-PIWIL4，HILI 2;HILI2;HIWI 2;HIWI2;Miwi 2 protein;Miwi2;PIWI;Piwi like 2;Piwi like ...的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

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