RNA聚合酶II抗体Anti-Pol II/RNA polymerase IIPOLR2A; POLR2; DNA directed RNA polymerase II A; DNA-directed RNA polymerase II largest su...
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性能参数：

中文名称：RNA聚合酶II抗体
英文名称：Anti-Pol II/RNA polymerase II
别名：POLR2A; POLR2; DNA directed RNA polymerase II A; DNA-directed RNA polymerase II largest su...
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：RNA polymerase II （Pol II） is an enzyme that is composed of twelve subunits ａnd is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The largest subunit of Pol II （referred to as RPB1 or RPB205） is a 1,840 amino acid protein that contains one C2H2-type zinc finger ａnd a C-terminal domain comprised of several heptapeptide repeats. Although Pol II function requires the cooperation of all twelve subunits, the largest subunit conveys Pol II catalytic activity and, together with the second largest subunit, forms the active center of the Pol II enzyme. Additionally, the large subunit participates in forming the DNA-binding domain of Pol II, a groove that is necessary for transcription of the DNA template. Without proper function of the large subunit, mRNA synthesis ａnd subsequent transcription elongation cannot occur.Subcellular Location : Nucleus.Similarity : Belongs to the RNA polymerase beta＇ chain family.

RNA聚合酶II抗体的质量标准：
浓度：1mg/1ml
交叉反应：hu, mo, rat, pig, cow, hrs, dog
产品类型：一抗
研究领域：细胞生物免疫学信号转导转录调节因子表观遗传学
蛋白分子量：predicted molecular weight: 217kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human Pol II/RNA polymerase II
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:50-200（石蜡切片需做抗原修复）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

RNA聚合酶II抗体Anti-Pol II/RNA polymerase II的相关产品目录：



（1mg/1mlRNA聚合酶II抗体Anti-Pol II/RNA polymerase II，POLR2A; POLR2; DNA directed RNA polymerase II A; DNA-directed RNA polymerase II largest su...的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

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