磷脂酸磷酸酯酶LPIN1抗体Anti-Lipin 1KIAA0188;LPIN1;PAP1;Phosphatidate phosphatase LPIN1....
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性能参数：

中文名称：磷脂酸磷酸酯酶LPIN1抗体
英文名称：Anti-Lipin 1
别名：KIAA0188;LPIN1;PAP1;Phosphatidate phosphatase LPIN1....
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 ａnd Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal （NLIP） domain ａnd a carboxy-terminal （CLIP） domain. LPIN1 （Lipin 1） is crucial for normal adipose tissue development ａnd metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation ａnd mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program ａnd suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation ａnd insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance ａnd lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia ａnd insulin resistance.

磷脂酸磷酸酯酶LPIN1抗体的质量标准：
浓度：1mg/1ml
交叉反应：mouse, Rat, Rabbit, Cow, Dog, Human, Pig, Chimpanzee
产品类型：一抗
研究领域：心血管细胞生物信号转导细胞周期蛋白糖尿病
蛋白分子量：predicted molecular weight: 99-110kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from mo Lipin 1
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
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磷脂酸磷酸酯酶LPIN1抗体Anti-Lipin 1的相关产品目录：



（1mg/1ml磷脂酸磷酸酯酶LPIN1抗体Anti-Lipin 1，KIAA0188;LPIN1;PAP1;Phosphatidate phosphatase LPIN1....的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

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