神经细胞死亡诱导蛋白激酶抗体Anti-TRIB3/p65 interacting inhibitor of NF-kappaBC20orf97; Neuronal cell death inducible putative kinase; Neuronal cell death-inducible put...
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性能参数：

中文名称：神经细胞死亡诱导蛋白激酶抗体
英文名称：Anti-TRIB3/p65 interacting inhibitor of NF-kappaB
别名：C20orf97; Neuronal cell death inducible putative kinase; Neuronal cell death-inducible put...
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Disrupts insulin signaling by binding directly to Akt kinases ａnd blocking their activation. May bind directly to ａnd mask the ＇Thr-308＇ phosphorylation site in AKT1. Binds to ATF4 ａnd inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA ａnd inhibits its phosphorylation ａnd thus its transcriptional activation activity. Interacts with MAPK kinases ａnd regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity.Tissue specificity:Highest expression in liver, pancreas, peripheral blood leukocytes ａnd bone marrow. Also highly expressed in a number of primary lung, colon ａnd breast tumors. Expressed in spleen, thymus, ａnd prostate ａnd is undetectable in other examined tissues, including testis, ovary, small intestine, colon, leukocyte, heart, brain, placenta, lung, skeletal muscle, ａnd kidney.Subcellular Location : Nucleus.Tissue Specificity : Highest expression in liver, pancreas, peripheral blood leukocytes ａnd bone marrow. Also highly expressed in a number of primary lung, colon ａnd breast tumors. Expressed in spleen, thymus, ａnd prostate ａnd is undetectable in other examined tissues, including testis, ovary, small intestine, colon, leukocyte, heart, brain, placenta, lung, skeletal muscle, ａnd kidney.Similarity : Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.Contains 1 protein kinase domain.Subunit : Interacts with AKT1, AKT2, ATF4, MAP2K1 ａnd MAP2K7.

神经细胞死亡诱导蛋白激酶抗体的质量标准：
浓度：1mg/1ml
交叉反应：hu, mo, rat, hrs, pig, chk, cow, dog, Rb
产品类型：一抗
研究领域：心血管细胞生物信号转导细胞凋亡细胞周期蛋白糖尿病细胞分化
蛋白分子量：predicted molecular weight: 40kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human TRIB3/p65 interacting inhibitor of NF-kappaB
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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神经细胞死亡诱导蛋白激酶抗体Anti-TRIB3/p65 interacting inhibitor of NF-kappaB的相关产品目录：



（1mg/1ml神经细胞死亡诱导蛋白激酶抗体Anti-TRIB3/p65 interacting inhibitor of NF-kappaB，C20orf97; Neuronal cell death inducible putative kinase; Neuronal cell death-inducible put...的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

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