α-甲基酰基辅酶A消旋酶抗体Anti-AMACR/P504Salpha-methylacyl-CoA racemase isoform 1; P504S; AMACR; CBAS4; P504S; RACE; 2 arylpropiony...
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中文名称：α-甲基酰基辅酶A消旋酶抗体
英文名称：Anti-AMACR/P504S
别名：alpha-methylacyl-CoA racemase isoform 1; P504S; AMACR; CBAS4; P504S; RACE; 2 arylpropiony...
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：alpha-methylacyl-CoA racemase（AMACR/P504S） is Prostate-specific antigen （PSA） screening for prostate cancer is now widespread in the United States among men of all ages. However PSA has limited specificity because benign disease, including prostatic enlargement ａnd inflammation, can increase PSA levels. Thus, a more specific prostate cancer markers is needed. One such potential marker is AMACR, an enzyme that is involved in peroxisomal beta-oxidation of dietary branched-chain fatty acids. Recent studies have shown that, compared with expression in normal or benign prostate epithelium, AMACR is consistently overexpressed in prostate cancer epithelium, making it a specific marker for cancer cells within the prostate gland. Furthermore, overexpression of AMACR may increase the risk of prostate cancer because its expression is increased in premalignant lesions （prostatic intraepithelial neoplasia）.Subcellular Location : Peroxisome. Mitochondrion.Similarity : Belongs to the CaiB/BaiF CoA-transferase family.AMACR的优点在于它是癌症特异性，在癌症组织中高表达。 AMACR亦可用作其他癌症的诊断标志物。对各种癌症细胞进行检查后发现，结肠直肠癌、卵巢癌、乳腺癌、膀胱癌、肺癌、淋巴瘤和黑素瘤都过度表达AMACR，以结肠直肠癌和前列腺癌表达。 AMACR是一种新型前列腺癌标记物，在前列腺癌中胞浆表达较多，正常表到较少.

α-甲基酰基辅酶A消旋酶抗体的质量标准：
浓度：1mg/1ml
交叉反应：mo, rat, hu
产品类型：一抗
研究领域：肿瘤免疫学
蛋白分子量：predicted molecular weight: 42kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from mouse AMACR N-terminus
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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α-甲基酰基辅酶A消旋酶抗体Anti-AMACR/P504S的相关产品目录：



（1mg/1mlα-甲基酰基辅酶A消旋酶抗体Anti-AMACR/P504S，alpha-methylacyl-CoA racemase isoform 1; P504S; AMACR; CBAS4; P504S; RACE; 2 arylpropiony...的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

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