肿瘤易感候选基因3抗体Anti-CASC3/MLN51Barentsz protein; Btz; Cancer susceptibility candidate gene 3 protein; Metastatic lymph no...
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中文名称：肿瘤易感候选基因3抗体
英文名称：Anti-CASC3/MLN51
别名：Barentsz protein; Btz; Cancer susceptibility candidate gene 3 protein; Metastatic lymph no...
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：The multiprotein exon junction complex （EJC） is deposited on mRNAs upstream of exon–exon junctions as a consequence of pre-mRNA splicing. In mammalian cells, this complex serves as a key modulator of spliced mRNA metabolism. MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer. The function of MLN51 in mammals remains elusive. Its fly homolog, named barentsz, as well as the proteins mago nashi ａnd tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte. Magoh ａnd Y14, the human homologs of mago nashi ａnd tsunagi, are core components of the exon junction complex （EJC）. The EJC is assembled on spliced mRNAs ａnd plays important roles in post-splicing events including mRNA export, nonsense-mediated mRNA decay, ａnd translation. Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes.

肿瘤易感候选基因3抗体的质量标准：
浓度：1mg/1ml
交叉反应：hu, mo, rat, hrs, cow
产品类型：一抗
研究领域：肿瘤免疫学信号转导
蛋白分子量：predicted molecular weight: 76kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human CASC3/MLN51
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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肿瘤易感候选基因3抗体Anti-CASC3/MLN51的相关产品目录：



（1mg/1ml肿瘤易感候选基因3抗体Anti-CASC3/MLN51，Barentsz protein; Btz; Cancer susceptibility candidate gene 3 protein; Metastatic lymph no...的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

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