Bcl2相关抗凋亡基因6抗体Anti-BAT3/BAG6family molecular chaperone regulator 6;BAG-6;BAG6;Bag6;BAG6_HUMAN;BCL2-associate...
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中文名称：Bcl2相关抗凋亡基因6抗体
英文名称：Anti-BAT3/BAG6
别名：family molecular chaperone regulator 6;BAG-6;BAG6;Bag6;BAG6_HUMAN;BCL2-associate...
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Chaperone that plays a key role in various processes such as apoptosis, insertion of tail-anchored （TA） membrane proteins to the endoplasmic reticulum membrane ａnd regulation of chromatin. Acts in part by regulating stability of proteins ａnd their degradation by the proteasome. Participates in endoplasmic reticulum stress-induced apoptosis via its interaction with AIFM1/AIF by regulating AIFM1/AIF stability ａnd preventing its degradation. Also required during spermatogenesis for synaptonemal complex assembly via its interaction with HSPA2, by inhibiting polyubiquitination ａnd subsequent proteasomal degradation of HSPA2. Required for selective ubiquitin-mediated degradation of defective nascent chain polypeptides by the proteasome. In this context, may play a role in immuno-proteasomes to generate antigenic peptides via targeted degradation, thereby playing a role in antigen presentation in immune response. Key component of the BAG6/BAT3 complex, a cytosolic multiprotein complex involved in the post-translational delivery of tail-anchored （TA） membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. BAG6/BAT3 acts by facilitating TA membrane proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins ａnd transfers them to ASNA1/TRC40 for targeting to the endoplasmic reticulum membrane.

Bcl2相关抗凋亡基因6抗体的质量标准：
浓度：1mg/1ml
交叉反应：hu, mo, rat
产品类型：一抗
研究领域：肿瘤细胞生物细胞凋亡
蛋白分子量：predicted molecular weight: 119kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from hu BAT3/BAG6
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
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Bcl2相关抗凋亡基因6抗体Anti-BAT3/BAG6的相关产品目录：



（1mg/1mlBcl2相关抗凋亡基因6抗体Anti-BAT3/BAG6，family molecular chaperone regulator 6;BAG-6;BAG6;Bag6;BAG6_HUMAN;BCL2-associate...的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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