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MDM2样P53蛋白结合抗体,Anti-MDMX,一抗 价格优惠 上海现货
点击次数:116发布时间:2012/7/12 22:37:01
更新日期:2013/5/6 16:06:32
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详细内容
MDM2样P53蛋白结合抗体Anti-MDMXDouble minute 4;Double minute 4 human homolog of p53 binding protein;Double minute 4 p...
360TIYO.COM-上海田源公司
性能参数:
中文名称:MDM2样P53蛋白结合抗体
英文名称:Anti-MDMX
别名:Double minute 4;Double minute 4 human homolog of p53 binding protein;Double minute 4 p...
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.Region I is sufficient for binding TP53 and inhibiting its G1 arrest and apoptosis functions. It also binds TP73. Region II contains most of a central acidic region and a putative C4-type zinc finger. The RING finger domain which coordinates two molecules of zinc mediates the heterooligomerization with MDM2.MDM2样P53蛋白结合抗体的质量标准:
浓度:1mg/1ml
交叉反应:hu, mo
产品类型:一抗
研究领域:细胞生物信号转导细胞凋亡表观遗传学
蛋白分子量:predicted molecular weight: 50-65kDa
性状:Lyophilized or Liquid
免疫原:KLH conjugated synthetic peptide derived from hu MDMX
亚型:polyclonal
纯化方法:affinity purified by Protein A
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用:WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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MDM2样P53蛋白结合抗体Anti-MDMX的相关产品目录:
(1mg/1mlMDM2样P53蛋白结合抗体Anti-MDMX,Double minute 4;Double minute 4 human homolog of p53 binding protein;Double minute 4 p...的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
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