腺苷单磷酸活化蛋白激酶α2抗体Anti-PRKAA2/AMPK alpha 2AMPK 2; AMPK2; AMPKalpha2; PRKAA 2; PRKAA; PRKAA2; Protein kinase AMP activated alpha 2 ca...
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性能参数：

中文名称：腺苷单磷酸活化蛋白激酶α2抗体
英文名称：Anti-PRKAA2/AMPK alpha 2
别名：AMPK 2; AMPK2; AMPKalpha2; PRKAA 2; PRKAA; PRKAA2; Protein kinase AMP activated alpha 2 ca...
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：The AMP activated protein kinase （AMPK） in mammals, ａnd its homologue in Saccharomyces cerevisiae, are activated by cellular stresses associated with ATP depletion. AMPK is a heterotrimer comprising a catalytic alpha subunit with associated beta ａnd gamma subunits. The alpha subunit has at least two isoforms （alpha 1 ａnd alpha 2）, which differ in their AMP dependence ａnd subcellular localization, with alpha 2 complexes being partly nuclear. AMPK is activated allosterically by 5＇ AMP, which also promotes phosphorylation ａnd activation by an upstream kinase, ａnd inhibits dephosphorylation ａnd inactivation. Elevation of AMP always accompanies depletion of ATP due to the action of adenylate kinase. Since high ATP antagonizes the activating effects of AMP, the system behaves like a cellular ＇fuel gauge＇. It is activated by various types of stress associated with ATP depletion, such as hypoxia, heat shock, metabolic poisoning and, in muscle, exercise. AMPK phosphorylates multiple targets which switch off anabolic pathways ａnd switch on alternative catabolic pathways.

腺苷单磷酸活化蛋白激酶α2抗体的质量标准：
浓度：1mg/1ml
交叉反应：hu, mo, rat, Rb, shp, cow, dog, pig
产品类型：一抗
研究领域：肿瘤信号转导激酶和磷酸酶
蛋白分子量：predicted molecular weight: 62kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human AMPK alpha 2 C-terminus
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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由于化学产品的特殊性，恕不接受以下投诉：
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腺苷单磷酸活化蛋白激酶α2抗体Anti-PRKAA2/AMPK alpha 2的相关产品目录：



（1mg/1ml腺苷单磷酸活化蛋白激酶α2抗体Anti-PRKAA2/AMPK alpha 2，AMPK 2; AMPK2; AMPKalpha2; PRKAA 2; PRKAA; PRKAA2; Protein kinase AMP activated alpha 2 ca...的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

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