凝血因子VIIAnti-Factor VII light chainCoagulation factor VII; Eptacog alfa; F7; FA7_HUMAN; Factor VII; Factor VII light chain; F...
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中文名称：凝血因子VII
英文名称：Anti-Factor VII light chain
别名：Coagulation factor VII; Eptacog alfa; F7; FA7_HUMAN; Factor VII; Factor VII light chain; F...
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 ａnd FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is an enzyme of the serine protease class. Factor VII contains two EGF-like domains, one Gla （gamma-carboxy-glutamate） domain ａnd one peptidase S1 domain. The main role of factor VII is to initiate the process of coagulation in conjunction with tissue factor （TF）. Tissue factor is found on the outside of blood vessels, normally not exposed to the blood stream. The action of the Factor VII is impeded by tissue factor pathway inhibitor （TFPI）, which is released almost immediately after initiation of coagulation. Factor VII is vitamin K dependent ａnd is produced in the liver. The use of warfarin or similar anticoagulants impairs its function. Upon vessel injury, tissue factor is exposed to the blood ａnd circulating Factor VII. Once bound to TF, FVII is activated to FVIIa by different proteases, among which are thrombin （factor IIa）, factor Xa, IXa, XIIa, ａnd the FVIIa-TF complex itself. The most important substrates for FVIIa-TF are Factor X ａnd Factor IX.Subcellular Location : Secreted.Tissue Specificity : Plasma.Similarity : Belongs to the peptidase S1 family.Contains 2 EGF-like domains.Contains 1 Gla （gamma-carboxy-glutamate） domain.Contains 1 peptidase S1 domain.Subunit : Heterodimer of a light chain ａnd a heavy chain linked by a disulfide bond.

凝血因子VII的质量标准：
浓度：1mg/1ml
交叉反应：hu, mo, rat, pig, hrs
产品类型：一抗
研究领域：心血管细胞生物
蛋白分子量：predicted molecular weight: 17/45kDa
性状：Lyophilized or Liquid
免疫原：KLH conjugated synthetic peptide derived from human Factor VII （61-105aa）
亚型：polyclonal
纯化方法：affinity purified by Protein A
储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（石蜡切片需做抗原修复）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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由于化学产品的特殊性，恕不接受以下投诉：
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凝血因子VIIAnti-Factor VII light chain的相关产品目录：



（1mg/1ml凝血因子VIIAnti-Factor VII light chain，Coagulation factor VII; Eptacog alfa; F7; FA7_HUMAN; Factor VII; Factor VII light chain; F...的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗）

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