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磷酸化腺苷单磷酸活化蛋白激酶β1抗体,Anti-phospho-AMPK beta 1(Ser108),一抗磷酸化抗体 价格优惠 上海现货
点击次数:160发布时间:2012/7/13 23:07:54
更新日期:2013/5/6 15:57:12
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详细内容
磷酸化腺苷单磷酸活化蛋白激酶β1抗体Anti-phospho-AMPK beta 1(Ser108)5 AMP activated protein kinase subunit beta 1; AMPK; AMPK beta 1 chain; AMPKb; HAMPKb; PRK...
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中文名称:磷酸化腺苷单磷酸活化蛋白激酶β1抗体
英文名称:Anti-phospho-AMPK beta 1(Ser108)
别名:5 AMP activated protein kinase subunit beta 1; AMPK; AMPK beta 1 chain; AMPKb; HAMPKb; PRK...
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.AMPKβ1(AMP-activated Protein Kinase beta-1)(腺苷单磷酸活化蛋白激酶β-1)是一种参与细胞适应能量危机的应激反应酶,AMPK不仅可以在细胞水平作为能量的感受器,还可以通过激素和细胞因子,如瘦素、脂联素和ghrelin来参与调节机体的能量消耗和能量摄入.磷酸化腺苷单磷酸活化蛋白激酶β1抗体的质量标准:
浓度:1mg/1ml
交叉反应:mo, rat
产品类型:一抗磷酸化抗体
研究领域:肿瘤细胞生物染色质和核信号信号转导细胞凋亡转录调节因子激酶和磷酸酶
蛋白分子量:predicted molecular weight: 30kDa
性状:Lyophilized or Liquid
免疫原:KLH conjugated Synthesised phosphopeptide derived from human AMPK beta 1 around the phosphorylation site of Ser108
亚型:polyclonal
纯化方法:affinity purified by Protein A
储存液:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用:WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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磷酸化腺苷单磷酸活化蛋白激酶β1抗体Anti-phospho-AMPK beta 1(Ser108)的相关产品目录:
(1mg/1ml磷酸化腺苷单磷酸活化蛋白激酶β1抗体Anti-phospho-AMPK beta 1(Ser108),5 AMP activated protein kinase subunit beta 1; AMPK; AMPK beta 1 chain; AMPKb; HAMPKb; PRK...的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
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