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磷酸化原癌基因c-Met相关酪氨酸激酶抗体,Anti-phospho-MST1R(Tyr1353),一抗磷酸化抗体 价格优惠 上海现货
点击次数:149发布时间:2012/7/14 15:54:09
更新日期:2013/5/6 15:45:30
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磷酸化原癌基因c-Met相关酪氨酸激酶抗体Anti-phospho-MST1R(Tyr1353)p-MST1R(Tyr1353);RON (phospho Y1353); MST1R(phospho S1349); c met related tyrosine kin...
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性能参数:
中文名称:磷酸化原癌基因c-Met相关酪氨酸激酶抗体
英文名称:Anti-phospho-MST1R(Tyr1353)
别名:p-MST1R(Tyr1353);RON (phospho Y1353); MST1R(phospho S1349); c met related tyrosine kin...
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:MST1R/Ron, a HGF Receptor/MET-type protein kinase, mediates the biological activities of macrophage-stimulating protein (MSP), a multifunctional cytokine that regulates cell adhesion, motility, growth, and survival. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers. Ron expression has been documented in many normal human tissues. ESTs have been isolated from several tissue libraries, including normal colon, mouth, prostate, and testis and cancerous colon, prostate, stomach, and uterus.磷酸化原癌基因c-Met相关酪氨酸激酶抗体的质量标准:
■别名: | p-MST1R(Tyr1353);RON (phospho Y1353); MST1R(phospho S1349); c met related tyrosine kin... |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗磷酸化抗体 |
■研究领域: | 肿瘤细胞生物信号转导转录调节因子激酶和磷酸酶 |
■蛋白分子: | predicted molecular weight: 152kDa |
■浓度: | 1mg/1ml |
■性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from hu phospho-MST1R(Tyr1353) |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■储存液: | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
■产品应用: | WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user. |
■保存条件: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化原癌基因c-Met相关酪氨酸激酶抗体Anti-phospho-MST1R(Tyr1353)的相关产品目录:
(1mg/1ml磷酸化原癌基因c-Met相关酪氨酸激酶抗体Anti-phospho-MST1R(Tyr1353),p-MST1R(Tyr1353);RON (phospho Y1353); MST1R(phospho S1349); c met related tyrosine kin...的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
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