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G蛋白β样蛋白抗体Anti-G protein beta subunit like
360TIYO.COM-上海田源公司
性能参数:
中文名称:G蛋白β样蛋白抗体
英文名称:Anti-G protein beta subunit like
别名:
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino-acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation.Tissue specificity:Broadly expressed, with highest levels in skeletal muscle, heart and kidney.G蛋白β样蛋白抗体的质量标准:
■别名: | |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■研究领域: | 细胞生物免疫学G蛋白偶联受体表观遗传学G蛋白信号 |
■蛋白分子: | |
■浓度: | 1mg/1ml |
■性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from hu G protein beta subunit like |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■储存液: | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
■产品应用: | ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user. |
■保存条件: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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G蛋白β样蛋白抗体Anti-G protein beta subunit like的相关产品目录:
(1mg/1mlG蛋白β样蛋白抗体Anti-G protein beta subunit like,的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗)
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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